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Genome-wide epigenetic studies of retinal disease, risk factors, and related pathologies.
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Genome-wide epigenetic studies of retinal disease, risk factors, and related pathologies.
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Genome-wide epigenetic studies of retinal disease, risk factors, and related pathologies.
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Genome-wide epigenetic studies of retinal disease, risk factors, and related pathologies.
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Summary of methods available for tumour suppressor methylation testing.
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Genome-wide epigenetic studies of retinal disease, risk factors, and related pathologies.

Journal: Journal of Experimental Neuroscience

Article Title: Epigenetic Mechanisms of the Aging Human Retina

doi: 10.4137/JEN.S25513

Figure Lengend Snippet: Genome-wide epigenetic studies of retinal disease, risk factors, and related pathologies.

Article Snippet: Ko et al, 2013 , Renal , Kidney fibrosis , Discovery: HELP-Nimblegen whole genome covering microarray; validation: bisulfite-Sequenom MassArray EpiTYPER; replication: Illumina Infinium HumanMethylation450K BeadChip , None , Discovery/validation: 12 hypertensive or diabetic chronic kidney disease, 14 controls; replication: 21 diabetic chronic kidney disease, 66 controls , Human kidney tubule epithelial cell tissue samples from healthy living transplants or surgical nephrectomies , Not provided , Discovery: 4751 DMRs/1535 genes; replication: 1061 genes , Cell adhesion, development , COLIVA1, DSCAM, DPT.

Techniques: Genome Wide, RNA Expression, Preserving, Methylation, Microarray, Immunohistochemistry, Western Blot, Activity Assay, Binding Assay, Methylated DNA Immunoprecipitation, Biomarker Discovery, DNA Methylation Assay, Cell Culture, Extraction, Methylation Sequencing, Transformation Assay, Sequencing, Methylated DNA Immunoprecipitation Sequencing, Phospho-proteomics, Glycoproteomics, Luciferase, Starch, In Vitro, Expressing, Transduction, Ubiquitin Proteomics, Clinical Proteomics, Membrane, Cell Differentiation, Control

Summary of methods available for tumour suppressor methylation testing.

Journal: Therapeutic Advances in Medical Oncology

Article Title: The role of aberrant DNA methylation in cancer initiation and clinical impacts

doi: 10.1177/17588359231220511

Figure Lengend Snippet: Summary of methods available for tumour suppressor methylation testing.

Article Snippet: Sequenom MassARRAY (EpiTYPER) , Bisulphite DNA , PCR of bisulphite DNA followed by base-specific cleavage and MALDI-TOF , High-throughput, (semi-) quantitative analysis of multiple CpG sites , Only average methylation level per CpG position.

Techniques: Methylation, Nucleic Acid Electrophoresis, DNA Methylation Assay, Amplification, Electrophoresis, Denaturing Gradient Gel Electrophoresis, High Performance Liquid Chromatography, Binding Assay, Radioactivity, Fluorescence, Combined Bisulfite Restriction Analysis Assay, Sequencing, Multiplexing, Microarray, Genome Wide, Bisulfite Sequencing, Nanopore Sequencing, Sampling, Methylated DNA Immunoprecipitation, Immunoprecipitation